This sample expert has over 40 years of experience, and specializes in the field of with specific knowledge in the areas of RNA, RNomics, RNA sequencing (RNAseq), gene and genome evolution, retrotransposition, transposable or repetitive elements, gene expression, recombinant proteins and transgenic, gene depleted, gene corrected mice, genome engineering. Published on such topics as RNA, gene and genome evolution, gene cloning, molecular neurobiology, mouse models for human genetic disease and evolution of life, ethical questions concerning our ability to engineer genomes. Testified on expression of recombinant proteins, expression vectors, transcription promoters, the repetitive nature of genomes.
Previously served as an expert witness in the areas of recombinant protein expression and the repetitive architecture of genomes. This expert’s experience with RNA (~3.5 decades) and having been one of the pioneers in RNomics is highly pertinent in patent issues concerning non-protein coding RNA (ncRNA), including miRNA, siRNA, CRISPR RNA, lincRNA etc., as well as RNA and its derivatives including aptamers for diagnostic and therapeutic applications.
This expert has a long standing interest in Molecular Evolution and provides a unique angle on the evolution of genes and genomes including de novo generation of genes or parts thereof, in addition to ethical questions concerning the powerful tools of medical genetic technology.
In the mid-nineties, this expert established a facility to generate transgenic and gene depleted/modified mice, which currently provides valuable mouse models for basic and clinical research.